Shaping Tomorrow through Biotechnological Innovation
GERMINAL BIOTECH PTE. LTD.
Forefront of innovation
Forefront of innovation
Antibody Discovery
Utilizing a meticulously refined workflow tailored for advanced display technologies, we have the capability to adeptly extract antigen-specific binders from diverse immune libraries spanning multiple species, which paves the way for developing therapeutics against different diseases.
Cell Line Establishment
Engineered cell lines are indispensable for many researches. We routinely generate overexpressing and knockout cell lines with both lentiviral and retroviral systems.
Humanization
Traditional humanization relies heavily on trial-and-error. We have integrated AI algorithms with high-throughput production system to identify the best humanized variants that retain parental affinity.
Affinity Maturation
When it comes to affinity maturation, yeast display is one of the most efficient platforms in a cost effective manner. We have crafted meticulously refined procedures for traditional random mutagenesis and saturated CDR scanning to identify the best variants with the desired affinity.
HDX
Hydrogen deuterium exchange (HDX) provides a fast and reliable method to identify your epitopes and paratopes. We have collaborated with real experts in the field and can generate a report within 2 weeks.
Developability Improvement
Not all antibodies were created equal. Some antibodies were simply not fit for further development into clinical candidates. Some of them can be optimized and rescued by leveraging the power of both computational and high-throughput approaches.
About Us
Innovation Passion Teamwork
GERMINAL BIOTECH PTE. LTD., founded in 2022, represents a pioneering force in the realm of therapeutic large molecules. Our core focus centers on the comprehensive discovery, development, and optimization of protein-based therapeutics.
With an unwavering commitment to innovation and excellence, our dynamic team of seasoned scientists collaborates closely with a network of esteemed partners. Together, we embark on a mission to provide the medical and scientific communities with the most robust, innovative, and transformative solutions.
Our approach to large molecule therapeutics encompasses the entire spectrum of discovery, from initial research and candidate identification to the intricate process of optimization. Through a combination of cutting-edge technologies, rigorous research, and a commitment to excellence, we strive to pave the way for the next generation of groundbreaking treatments.
GERMINAL BIOTECH is dedicated to advancing the field of protein-based therapeutics and contributing to the betterment of human health on a global scale. Our vision is to lead the industry in delivering safe, effective, and innovative solutions to address unmet medical needs.
Shaping Tomorrow through Biotechnological Innovation
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Get in touch
harryzhao@germinalbiotech.com
admin@germinalbiotech.com
25 International Business Park,
#01-68/75 German Centre,
Singapore 609916